Exploring oxidovanadium(<scp>iv</scp>) homoleptic complexes with 8-hydroxyquinoline derivatives as prospective antitrypanosomal agents

Scalese Gonzalo, Machado Ignacio, Correia Isabel, Pessoa Joao Costa, Bilbao Lucía, Pérez-Diaz Leticia, Gambino Dinorah
New Journal of Chemistry . 2019, 43 (45), 17756-17773;
http://dx.doi.org/10.1039/c9nj02589h | Referencias: 93

[V^IVO(L-H)₂] and [V^VO(OCH₃)(L-H)₂] compounds of 8-hydroxyquinoline derivatives L showed activity againstTrypanosoma cruziandLeishmania infantumand high selectivities. Metallomics and interaction with BSA, apo-HTF and DNA were studied.