Multifunctional organometallic compounds for the treatment of Chagas disease: Re(<scp>i</scp>) tricarbonyl compounds with two different bioactive ligands

Soba Mariano, Scalese Gonzalo, Casuriaga Federico, Pérez Nicolás, Veiga Nicolás, Echeverría Gustavo A., Piro Oscar E., Faccio Ricardo, Pérez-Díaz Leticia, Gasser Gilles, Machado Ignacio, Gambino Dinorah
Dalton Transactions . 2023, 52 (6), 1623-1641;
http://dx.doi.org/10.1039/d2dt03869b | Referencias: 96

Multifunctional Re(i) tricarbonyls including phenanthroline derivatives and Clotrimazole showed high activity against Trypanosoma cruzi and inhibited parasite lanosterol 14-α-demethylase (CYP51)...Leer más